Bioreactor for cell culture 450L

SYSBIOTECH fully automated bioreactor was designed especially for cell culture cultivation. Design and manufacturing was made according to GMP requirements.

For gentle and efficient mixing our engineers applied pitch blade impellers with magnetic drive and spin-filter.

Bioreactor is equipped with gas-mixing system for sparging and overlay: Air, Oxygen, Nitrogen, CO₂.

Sterilization procedure is carried out in fully automatic mode. This bioreactor is equipped with additional SIPable feeding lines.

It is possible to provide on-line measurement of media composition using SYSBIOTECH SCADA system.

Bioreactor is mounted on stainless steel tubular legs with adjustable feet. Manual bypass line controls the flow-rate of each gas automatically.

Total volume	450L
Materials	AISI 316L, CIP armature, magnetic agitator
Temperature	Internal working temperature: 15-143°C
Pressure Vessel Code	2014/68/EU
Surface inside	cold rolled 2B, Ra≤0.4 μm, electropolished
Surface outside	cold rolled 2B
Sparger inlet	Air, O2 and CO2 = 0.3 x VVM
Head Space	Air, O2 and CO2 = 0.05 x VVM
Agitation speed	10-120 rpm
Top lid	Flat plate with lifting system

C-BIO2^TM control system features:

Universal control system for bioreactors of any volume.
You can use either separate control system for each culture vessel, or one control system for several vessels.
The system is based on SCADA controller, constructed in conformance with industrial automation standards.
Simple and intuitive user interface provides quick access to all controllers and data.
You can create your own program of cultivation using “Sequences” program – for better control of your bioprocess.
All bioprocess data is gathered and saved as separate electronic records.
To minimize the number of errors, different bioreactor operators have four different levels of access to the control system.

Bioreactor for cell culture 450L

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Bioreactor for cell culture 450L

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