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SYSBIOTECH Pilot-scale Fermenters are a reliable solution for working with microbiological cultures for scientific research or small biotech production facilities, as well as for scaling-up technology.
Standard «ready to use» solutions include all components needed for convenient operation with microbial culture applications. After connecting the Fermenter you can start using it right away without having to buy any accessories.
SYSBIOTECH Pilot scale Fermenters have fully aseptic design and can be validated easily. C-BIO2 control system, universal for any volume of Fermenter greatly simplifies scale-up process and allows for easy transfer of fermentation data.
If needed, SYSBIOTECH Fermenters can be upgraded to fulfill your specific application requirements.
For your convenience, all the necessary piping is installed on open stainless steel mobile frame. This helps to save space in your facility and simplifies access for maintenance of the Fermenter.
All wetted surfaces are made of AISI 316L stainless steel with surface finish of 0.8 μm, to allow for effective CIP (cleaning-in-place).
Automated and user-configurable CIP and SIP (cleaning-in-place and sterilization-in-place) processing are standard included. A user-friendly program tool allows you to create your CIP and/or SIP sequence by defining its steps and set parameters. By combining sequences you can build a fully automated procedure for your entire application, maximizing day to day process consistency and ensuring best results.
Vessel (High/Diameter: 3/1)
|Materials||AISI 316L for wetted parts
AISI 304L for non-wetted parts
|Design pressure||3.0 kg/cm3 (vessel)
4.0 kg/cm3 (jacket)
|Design temperature||143°С (vessel)
|Surface finish||Internal polishing Ra 0.8 μm
External polishing Ra 1.2 μm
|Top lid||Diaphragm Pressure Gauge|
|Diaphragm Pressure Transmitter|
|Rupture disk with outlet pipe|
|Gases exhaust with condensor|
|Foam control with peristaltic pump|
|CIP spray ball|
|Upper side walls||Air inlet|
|Sparger (ring or micro sparger)|
|Lower side walls||Temperature sensor PT100|
|pH control with peristaltic pumps|
|Sterile sampling system|
|Different sensors available on request: optical density, ORP, level, weight, conductivity, pCO2|
|Jacket||Steam inlet / Cooled water outlet|
|Steam outlet / Cooled water supply
(with safety valve and manometer)
|Bottom||Sterializable bottom valve|
|Agitation unit||Single mechanical or magnetic seal|
|Manual/automatic speed control depending on the amount of dissolved oxygen.|
|Speed range 30-600 RPM. Up to 1.500 RPM available on request|
|Marine, Rushton or pitched-blade impeller. Different impeller types available on request|
|3 welded baffles|
|Aeration unit||Automatic air supply 2 VVM|
|5" absolute filter 0.2 μm and filter housing made from AISI 316L stainless steel|
|Manual flow meter or automatic MFC (mass flow controller)|
|Piping||Material||Sanitary grade steel|
|Piping construction||Air supply|
|Plant steam supply|
|Pure steam supply|
|Cooling water supply|
|Cooling water return|
|Waste water drain|
|Waste liquid drain|
|Waste gas out|
|Angle seat valve|
|Diaphragm pressure gauge|
|Ball valve and Pneumatic angle valve|
|Pipes welding||Orbital welding (product line)|
|Manual welding (general line)|
C-BIO2TM control system features: