IsoPharm Bioprocess Analyzer - Sysbiotech buttons
Mooslackengasse 17, 1190 Vienna Austria
+43 660 990 4409

IsoPharm Bioprocess Analyzer


IsoPharm Near-infrared (NIR) systems are designed for online monitoring in biopharmaceutical production. You may monitor your fermentation and cell culture bioreactors in real time. IsoPharm Analyzers can be a key part of Process Analytical Technology (PAT) and Quality by Design (QbD) projects. With easy integration into existing control systems, achieving new targets in quality control and cost savings is possible.

Biopharmaceutical production processes, including microbial fermentation and mammalian cell culture cultivation vary greatly with organisms behaving differently and metabolizing at varying rates. With in-process measurements you can monitor the key parameters and optimize the fermentation or cell culture processes.

Using the IsoPharm Bioprocess Analyzer allows for rapid analysis of many different properties with one quick measurement.

Both Fermentation and Cell Culture processes in a closed vessel can benefit greatly from in-process or in situ chemical analysis. Whether you are working with small laboratory scale reactors or large scale production equipment, the analyzer makes your processes more efficient and optimized. The IsoPharm provides useful analysis for R&D, Scale-up, Process Development and full-scale production. Large-scale fermenters and bioreactors can hold as many as 1 000 000 L of raw material, which may be in process for hours or several weeks. The IsoPharm Analyzer can monitor both the start-up media and the accumulated product on-line, despite the thick, viscous nature of the medium.

Online analysis is nondestructive, automated and done in seconds, with results sent to your DCS, PLC, or LIMS. LT-NIR can help aid process improvement in several areas:

  • Validate quality throughout the process—Determine where and when product falls out of specification
  • Make process adjustments in real time—Reduce waste by adjusting process conditions
  • Reduce energy use and increase process efficiency—Accurately determine when reactions are complete
  • Design quality into your process—Achieve higher standards than with batch testing
Industrial-scale bioreactor 500-1000L
Pro-Lab control system bioreactors
Full-size CIP/SIP Fermenters 150L-300L-500L
Process vessel with CIP and SIP – 250L