Compact CIP/SIP Fermenters 15L-50L-100L

SYSBIOTECH Pilot-scale Fermenter is a reliable solution for working with microbial process for scientific research, small biotech production facilities as well as for scaling-up.

Standard «ready to use» solutions include all components needed for convenient operation with microbial cultures. After connecting the Fermenter you can start using it right away without having to buy any accessories.

SYSBIOTECH Pilot-scale Fermenters have fully aseptic design and can be validated easily. C-BIO2 control system, universal for any volume of Fermenter greatly simplifies scale-up process and allows for easy transfer of fermentation data.

If needed, SYSBIOTECH Fermenters can be upgraded to fulfill your specific application requirements.

Popular models	Total volume (L)	Working volume (L)	Minimal volume (L)
SYSBIOTECH 15 L	15	10.5	4
SYSBIOTECH 20 L	20	14	5
SYSBIOTECH 30 L	30	21	5

For your convenience, all the necessary piping is installed on open stainless steel mobile frame. This helps to save space in your facility and simplifies access for maintenance of the Fermenter.

All wetted surfaces are made of AISI 316L stainless steel with surface finish of 0.6 μm, to allow for effective CIP (cleaning-in-place).

Automated and user-configurable CIP and SIP (cleaning-in-place and sterilization-in-place) processing is standard included. A user-friendly program tool allows you to create your CIP and/or SIP sequence by defining its steps and set parameters. By combining sequences you can build a fully automated procedure for your entire application, maximizing day to day process consistency and ensuring best results.

Vessel (Height : Diameter = 2:1 or 3:1)
Materials	AISI 316L for wetted parts
	ASISI 304L for non-wetted parts
Design pressure	3.0 kg/cm³ (vessel)
	4.0 kg/cm³ (jacket)
Design temperature	143°С (vessel)
	151°С (jacket)
Surface finish	Internal polishing 0.4 μm (electropolished)
	External polishing 1.2 μm
Components
Top lid	Diaphragm Pressure Gauge
	Diaphragm Pressure Transmitter
	Rupture Disk
	Gases exhaust with condensor
	Agitation system (if upper agitation is chosen)
	Inoculation port
	Level sensor
	Foam sensor
	CIP Spray Ball
	Sight glass+light
Upper side walls	Gases supply
	Viewing glass
	Additional feedings
	Sparger (ring or micro sparger)
Lower side walls	Temperature sensor
	pH sensor
	pO₂sensor
	OD sensor
	Sampling port
	Spare ports
Jacket	Temperature control system
	Vessel insulation jacket
Bottom	Common drain and biowaste drain via sterilizable bottom valve (self-drainable)
	Agitation system (if bottom agitation is chosen)
Agitation unit
	Single/double mechanical or magnetic seal
	Manual/automatic speed control depending on the amount of dissolved oxygen
	Speed range 10–800 rpm. Up to 1,500 rpm available upon request
	Marine, Rushton or pitched-blade impeller. Different impeller types available upon request
	3-4 welded or removable baffles

	Automatic air supply up to 2 vvm
	PTFE absolute filter 0.2 μm and filter housing made from AISI 316L stainless steel
	Manual flow meter or automatic MFC
Piping
Material	Sanitary grade steel
Piping construction	Air supply
	Plant steam supply
	Pure steam supply
	Cooling water supply
	Cooling water return
	Common drain
	Biowaste drain
	Exhaust out
Fittings	Diaphragm valve
	Angle seat valve
	Steam trap
	Diaphragm pressure gauge
	Ball valve
	Check valve
	Safety valve
Pipes welding	Orbital welding (product line)
	Manual welding (general line)

Main features:

Ready-to-work standard solutions with the ability to upgrade.
100% aseptic design, easy validation.
Different types of impellers: Rushton, marine-blade, pitched-blade right- and left-handed orientation with radial or axial flow.
Motor with single mechanical or magnetic seal guarantees 100% aseptic operation.
Mixing speed 30–600 rpm (standard option); up to 1,500 rpm upon request.
Standard sensors: temperature, pH, pO₂, and foam.
Sensors upon request: OD, ORP, level, weight, conductivity, pCO₂, gas analyzers.
5" absolute filters 0.2 μm to ensure purity of gas mixture inside the vessel.
Manual flow meter or automatic mass flow controller (MFC) to regulate supply of gas mixture.
Different sparger types including ring- or micro-spargers. Various specific designs are available upon request.
Two in-gold ports for housing any required electrodes.

C-BIO2^TM control system features:

Universal control system for SYSBIOTECH’s fermenters and/or bioreactors, independent of volume.
You can use either separate control system for each culture vessel, or one control system for several vessels (parallel experiments, individual vessel control).
The system is based on SCADA controller, constructed in conformance with industrial automation standards.
Simple and intuitive user interface provides quick access to all controllers and data.
Automation of the entire cultivation procedure using pre-programmed ‘sequences’ –for better control of your bioprocess.
The SCADA software ensures easy and reliable data management and control across all platforms.
Four level password control is included, to allow for administrator, manager, supervisor and user level authorization.

Compact CIP/SIP Fermenters 15L-50L-100L

RECOMMENDED PRODUCTS

TECHNOLOGICAL SCHEME

Compact CIP/SIP Fermenters 15L-50L-100L

RECOMMENDED PRODUCTS

TECHNOLOGICAL SCHEME

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